April is Parkinson’s Awareness Month, serving as an opportune time to explore the significant influence dietary patterns and food choices have on neurodegenerative disease and prevention.
Both our lifestyle and exposure to certain environmental factors can lead to the injury and eventual death of brain cells that produce a neurotransmitter called dopamine. Dopamine is one of the brain's "feel-good" chemicals that helps control how you move, stay motivated, and feel pleasure. But if the part of your brain that makes dopamine starts losing cells fast, especially in a place called the substantia nigra, it may lead to Parkinson’s disease (PD).1
Close to one million people in the United States are currently living with Parkinson's disease, a number that is expected to rise rapidly each year.1 As this number grows, many are left wondering what's behind the acceleration in Parkinson's cases. One noteworthy factor that continues to gain attention is how we eat.
Whether you’ve witnessed a loved one's struggle or face a diagnosis yourself, research reveals that dietary choices can be a powerful tool to help manage — and even possibly prevent — Parkinson’s Disease. Read on to learn about the latest breakthroughs in diet for Parkinson’s prevention.
What Causes Parkinson’s Disease?
Roughly 5-10% of Parkinson's cases can be attributed to genetics as the major factor.2
The rest of Parkinson’s cases are “sporadic” and attributed to several risk factors, including environmental causes, such as exposure to pesticides and herbicides increasing the likelihood of developing the disease, one specific chemical being trichloroethylene (TCE), a solvent commonly used for dry cleaning.3 Another factor is severe head trauma (like concussions), which increases Parkinson's risk by 50%.4
Additionally, there is one very common risk factor that many of us share: diet.
Renowned neurologist and researcher, Dr. Matthew Phillips, has spearheaded the understanding of how our diets stand out as a major modifiable factor that can significantly impact disease risk, whether you're looking to manage Parkinson's disease or help prevent it. And the research continues to mount, suggesting our diets are pivotal in disease prevention, let alone overall cognitive health.
This naturally leads us to ask: what dietary choices should I make?
Understand How Dietary Choices Can Impact Parkinson’s
As we cover in a separate article, metabolic health can play a significant role in the risk of developing Parkinson's disease (and managing its symptoms). Another intriguing perspective lays in our mitochondrial function, where mitochondrial dysfunction has now been named a hallmark of PD.5 Mitochondria are the little organelles floating inside our cells that produce energy to power our cells, which is crucial to our health and survival!
Both metabolic and mitochondrial health are heavily influenced by our dietary habits and choices. The foods we consume provide the nutrients, vitamins, and minerals necessary for cellular metabolism (all essential chemical processes in cells) and energy production. Therefore, how and what we choose to eat can significantly impact brain cells and other cells (such as in the gut) that contribute to the risk of developing Parkinson's disease or its progression.
Top 10 Dietary Strategies and Food Choices for Parkinson’s
Choosing a Dietary Pattern
The Western diet, often called the Standard American Diet (SAD), is a major risk factor for neurodegenerative diseases like Parkinson's. For those of us living in the United States, almost all of us are on the SAD to some extent. The SAD is high in excess calories, saturated fats, and sugars, while low in healthy fats and fiber — think ultra-processed foods.6 Given its detrimental effects, it is imperative to explore healthier dietary patterns that aim to prevent and alleviate Parkinson's disease risk and symptoms.
“Looking at Parkinson’s disease from a metabolic perspective is an exciting research area and no longer a fringe idea. The NIH and other researcher groups are actively investigating metabolic approaches and dietary interventions as an extension of how we treat, reduce risk, and potentially even prevent Parkinson’s. Diet and nutrition are critical to our metabolic health, and it can go one of two ways. Diet can either sabotage our health, or it can serve as a very potent tool for its improvement. Our daily choices and the tools we use will dictate the trajectory it takes.” - Zoltan Mari, MD, Lou Ruvo Center for Brain Health, NeuroReserve Medical Advisor
So, how do we know what's considered a "healthy dietary pattern"?
A healthy dietary pattern simply means any eating style that research is showing can help people live longer and have better health and quality of life.7 The following are three dietary patterns that have shown to assist in Parkinson’s prevention and management.
1. Mediterranean Diet (MeDi)
The MeDi has long been recommended for many health conditions, so it's no surprise that it has been ranked as the #1 diet for the 6th year in a row.8
This dietary pattern is characterized by a high intake of extra virgin olive oil, fresh vegetables and fruits, fish, whole grains, legumes, seeds, and nuts, with limited amounts of red meat and saturated fats (such as from fast food and packaged snacks).
The MeDi is rich in vitamins, omega-3 fatty acids, polyphenols, and antioxidants, which also have potent anti-inflammatory properties.
Studies have shown that those who eat most closely to the MeDi, have about a 25% risk reduction of Parkinson’s disease with an even stronger 33% lower probability of developing prodromal (pre-symptomatic) PD.9
It’s important to note that the greater the adherence to Mediterranean styles of eating, the stronger the protection against Parkinson’s disease.9
2. Green Mediterranean Diet
The Green MeDi diet, as its name implies, draws inspiration from the traditional MeDi while placing a greater emphasis on plant-based foods. The Green MeDi also incorporates tea as a foundational component.
Research shows that embracing a plant-based dietary approach like the Green MeDi may lower risk of developing Parkinson's disease by 22%.10
3. MIND Diet: Mediterranean-DASH Intervention for Neurodegenerative Delay
The MIND diet is a unique fusion of the Mediterranean and DASH (Dietary Approaches to Stop Hypertension) diets.
DASH is an eating plan specifically designed to lower blood pressure through dietary modifications. The MIND diet takes a more targeted approach by focusing on foods that are particularly beneficial for brain health — such as dark leafy green vegetables and berries.
Studies have found that adhering to the MIND diet is associated with up to 42% lower risk of incident Parkinsonism (symptoms related to Parkinson’s) and progression.11
Most recently, a 2026 study highlighted up to 25% lower risk of developing PD specifically in women under the age of 71 through adherence to MIND and Mediterranean patterns of eating, with legumes and a high unsaturated-to-saturated fat ratio offering the strongest protective effects.12
This way of eating also naturally provides essential nutrients involved in brain cell protection and repair, such as folate, vitamin B12, and B6. Another recent study highlights how these nutrients may help reduce Parkinson’s risk, with a 17-29% risk reduction in those with higher intake — particularly in individuals at high genetic risk of developing PD.13
Food can serve as powerful medicine when used to your advantage. But when life gets hectic, sticking to a consistent diet can be a challenge. With nutritional supplementation, you can provide your body with the nutrients you need beyond what you eat. RELEVATE, NeuroReserve’s flagship brain health product, contains 17 clinically researched nutrients designed to support long-term brain health. These nutrients are selected based on those found in brain-healthy diets such as the Mediterranean and MIND patterns of eating.
RELEVATE helps bridge the gap between the ideal intake of nutrients for brain health and the Standard American Diet (SAD). The founder of RELEVATE, Dr. Edward Park, was inspired to create this solution after witnessing his father's early-onset Parkinson's diagnosis and realizing the potential role of the SAD in contributing to such conditions.
Be sure to also explore Brain Health Kitchen Extra Virgin Olive Oil (BHK EVOO) for a premium, organic olive oil that’s high in brain-protective polyphenols to double-down on a Mediterranean-style diet.
4. Adding a Ketogenic Approach to the Above Diets
Building upon the strategies discussed earlier, you can further consider integrating ketogenic approaches into any one of the diets listed earlier. Ketogenic approaches are characterized by low-carbohydrate, high-fat compositions, which induce a state of “fasting” and “ketosis,” where the body produces ketone bodies from fat as an energy source, instead of using carbohydrates. Ketone bodies not only serve as fuel, but they also promote resistance to oxidative and inflammatory stress, as well as improve the health of mitochondria.14
A randomized controlled trial (RCT) indicated that individuals with Parkinson’s adhering to a ketogenic approach experienced a 41% improvement in various non-motor symptoms, including urinary problems, pain, fatigue, daytime sleepiness, and cognitive impairment.15 Furthermore, a 2025 review suggested that a ketogenic approach may improve non-motor symptoms through anti-inflammatory effects, enhanced mitochondrial function, and changes in the gut microbiome.16
Rather than viewing the keto diet as a standalone way of eating, applying ketogenic principles to an overarching diet, like the Mediterranean, may strike the right balance for brain health. While ketogenic approaches typically emphasize higher fat intake as a fuel source, it’s important to note that the kind of fat we eat is important. Healthy monounsaturated fats from extra virgin olive oil and avocado oil or polyunsaturated fats such as omega-3s are great options.
Here are a couple of low-carb, high-fat ways to start implementing a keto approach to your diet:
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Choose leafy greens and other vegetables as your grain's replacement.
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Snack on hard boiled eggs, olives, nuts, seeds, and other low carb options.
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For a sweet treat, eat some berries, or explore alternative sugar substitutes, like monk fruit sweetener or date sugar.
If you want to learn more about how to practice a ketogenic approach to a brain-healthy diet, let us know and we’ll write more about it!
5. Consider Time-Restricted Eating to Get Your Body into a “Fasted” State
Another strategy gaining attention is time-restricted eating, which involves setting a daily window of time where no food is consumed. Typically, this fasting period lasts 12 hours or more (often overnight), allowing the body to enter a “fasted” state and begin a “switchover” from using carbohydrates to ketone bodies for fuel.17
As we discussed earlier, mitochondrial dysfunction is a primary factor in Parkinson's disease. Time-restricted eating may help address this issue by giving mitochondria the opportunity to rest, potentially slowing the pathology, symptoms, and cognitive decline associated with Parkinson's.
Fasting periods can range from 12 to 18 hours daily, or up to a full 24 hours every other day, with normal eating patterns on alternate days.18 Entering a “fasted” state boosts ketone bodies, providing brain cells with an alternative energy source and helping to overcome brain insulin resistance, which is common in Parkinson's patients. This can also trigger BDNF (which supports the creation of new brain cells), reduce inflammation, and promote beneficial genetic changes. Crucially, it may help restore mitochondria.19
New research reveals that the type of protein consumed while following a time-restricted eating schedule may also matter. Specifically, plant-based protein such as soy (which is often emphasized in plant-forward diets like the Green Mediterranean Diet) may support dopamine levels and help reduce inflammation by increasing beneficial bacteria in the gut — an area of growing interest in Parkinsons’s disease management.20
Additions for Your Parkinson’s Pantry
Now that we've explored various dietary approaches, let's zero in on specific foods and nutrients that can be particularly beneficial for individuals with Parkinson's or those interested in prevention.
6. Polyphenol- and Flavonoid-Rich Foods
Polyphenols and flavonoids have gained attention for their significant role in protecting brain health. Known for their antioxidant and anti-inflammatory properties, these plant compounds can powerfully support Parkinson’s prevention and management.
Your morning drink of choice may be contributing to brain health more than you think. Green tea contains high levels of catechin-rich polyphenols, which have been shown to reduce dopamine loss.21
Additionally, studies have shown that drinking coffee daily, even during mid-life, can reduce the risk of developing Parkinson's disease by 80% compared to non-coffee drinkers; the caffeine in coffee is suspected to be the active compound.22 Coffee (and the caffeine in it) may be achieving this by reducing brain cell inflammation, keeping the blood-brain barrier strong, and lowering the loss of certain brain cells connected to dopamine.22
Berries — especially blueberries, blackberries, and strawberries— are another rich source of brain-supportive compounds, particularly flavonoids. Berries contain flavonoids such as anthocyanins, quercetin, and catechins, which have implications on Parkinson's disease.23
Research indicates that individuals who consume high levels of flavonoids are 40% less likely to develop Parkinson’s.24
7. Fiber
Fiber is essential for smooth digestion, and it plays a surprising role in Parkinson’s disease and prevention. Beyond alleviating common gut issues like constipation — which is common in Parkinson's patients — it offers another powerful effect. Fiber can increase the production of short-chain fatty acids (SCFAs) in the gut by feeding certain types of bacteria. In fact, one of these SCFAs, called propionate, has recently been shown as a potentially potent protector of intestinal energy that fights Parkinson’s disease-related neurodegeneration.25
A specific type of fiber called resistant starch has also shown particularly promising results in PD management. A 2025 study of patients with Parkinson’s discovered that long-term resistant starch intake increased beneficial bacteria and SCFAs while reducing inflammation — which led to improvements in PD symptoms and quality of life.26 Foods containing resistant starch include legumes, lentils, oats, green bananas, and cooked and cooled potatoes.
8. Nuts
Next time you reach for a handful of trail mix, know that you're not just snacking on the go, but also lowering your risk of Parkinson’s. The nuts in trail mix contain a high amount of Vitamin E, which can contribute to protection against Parkinson's disease.
In fact, a study found that people who consumed the most Vitamin E had a 32% lower risk of Parkinson's disease.27 Vitamin E activates cellular pathways involved in antioxidant, detoxifying, and anti-inflammatory responses, while also promoting energy production at the mitochondrial level.28
The nutritional supplement RELEVATE brings together the recommendations mentioned above, making it easier to integrate these suggestions into daily routines. With key ingredients like catechins, flavonoids, vitamin E, and other brain-supportive nutrients in high-quality forms, it offers a convenient option to supplement your nutritional needs.
9. Be Mindful of Dairy Intake
Dairy products are often considered a part of a healthy diet due to their benefits for bones, muscles, immunity, and more. However, recent research has explored its connection to Parkinson’s disease, suggesting higher intake may increase risk. More specifically, a high consumption of low-fat dairy foods was associated with 30% increased PD risk, and the overall association was stronger in men than women.29
This does not mean you should eliminate dairy from your diet; it just highlights the importance of moderation — especially if you have other risk factors for Parkinson’s disease. Consider emphasizing plant-based alternatives as well as the other protective foods discussed throughout this article.
10. Time Your Meals with Medications
If you've already been diagnosed with Parkinson's disease, following the dietary recommendations mentioned earlier can still be helpful. However, there are additional factors to consider, especially when it comes to timing meals around medication.
Levodopa, a common Parkinson's medication, is typically taken multiple times a day and is recommended 30 minutes before or 1-2 hours after eating.30 This makes meal timing a crucial part of optimizing treatment and nutrition.
Additionally, it's important to pay attention to the composition of your meals. Heavy protein meals can lead to what's known as the "protein effect," where dietary protein interferes with the absorption of levodopa.30 This occurs because levodopa and dietary protein both share similar amino acids for transport into the bloodstream and brain, and in some cases, there aren’t enough transporters to go around.30 Being mindful of meal timing and protein intake can therefore help support the effectiveness of your medication.7
The journey to lifelong brain health can be approached with leaps or small steps. But if you commit to it wholeheartedly, progress is inevitable. So, take that first step and keep moving forward with determination — every effort counts on the path toward a healthier brain, brighter future, and better quality of life.
Interested in more brain-healthy tips? Sign up here for our newsletter and get a FREE e-guide to help you learn how to eat the Mediterranean way — plus, receive evidence-based articles, tips, and recipes directly to your inbox.
References
-
Understanding Parkinson’s | Parkinson’s Foundation. (n.d.). Retrieved March 24, 2024, from https://www.parkinson.org/understanding-parkinsons
-
Jia, F., Fellner, A., & Kumar, K. R. (2022). Monogenic Parkinson’s Disease: Genotype, Phenotype, Pathophysiology, and Genetic Testing. Genes, 13(3). https://doi.org/10.3390/GENES13030471
-
Hancock, D. B., Martin, E. R., Mayhew, G. M., Stajich, J. M., Jewett, R., Stacy, M. A., Scott, B. L., Vance, J. M., & Scott, W. K. (2008). Pesticide exposure and risk of Parkinson’s disease: A family-based case-control study. BMC Neurology, 8, 6. https://doi.org/10.1186/1471-2377-8-6
-
Rugbjerg, K., Ritz, B., Korbo, L., Martinussen, N., & Olsen, J. H. (2008). Risk of Parkinson’s disease after hospital contact for head injury: population based case-control study. The BMJ, 337(7685), 34–36. https://doi.org/10.1136/BMJ.A2494
-
Henrich, M. T., Oertel, W. H., Surmeier, D. J., & Geibl, F. F. (2023). Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential. Molecular Neurodegeneration 2023 18:1, 18(1), 1–20. https://doi.org/10.1186/S13024-023-00676-7
-
Jackson, A., Forsyth, C. B., Shaikh, M., Voigt, R. M., Engen, P. A., Ramirez, V., & Keshavarzian, A. (2019). Diet in Parkinson’s Disease: Critical Role for the Microbiome. Frontiers in Neurology, 10, 489352. https://doi.org/10.3389/FNEUR.2019.01245/BIBTEX
-
Knight, E., Geetha, T., Burnett, D., & Babu, J. R. (2022). The Role of Diet and Dietary Patterns in Parkinson’s Disease. Nutrients, 14(21). https://doi.org/10.3390/NU14214472
-
Burdeos, R. L. J. Top Expert-Recommended Diets Overall. U.S. News and World Report https://health.usnews.com/best-diet/best-diets-overall (2026).
-
Zhao, J., Peng, Y., Lin, Z. & Gong, Y. Association between Mediterranean diet adherence and Parkinson’s disease: a systematic review and meta-analysis. J. Nutr. Health Aging 29, 100451 (2025).
-
Tresserra-Rimbau, A., Thompson, A. S., Bondonno, N., Jennings, A., Kühn, T., & Cassidy, A. (2023). Plant-Based Dietary Patterns and Parkinson’s Disease: A Prospective Analysis of the UK Biobank. Movement Disorders, 38(11), 1994–2004. https://doi.org/10.1002/MDS.29580
-
Agarwal, P., Wang, Y., Buchman, A. S., Holland, T. M., Bennett, D. A., & Morris, M. C. (2018). MIND Diet Associated with Reduced Incidence and Delayed Progression of Parkinsonism in Old Age. The Journal of Nutrition, Health & Aging, 22(10), 1211–1215. https://doi.org/10.1007/s12603-018-1094-5
-
Hajji‐Louati, M. et al. Adherence to the Mediterranean and Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay ( <scp>MIND</scp> ) Diets and Parkinson’s Disease Incidence in Women: Results from the Prospective <scp>E3N</scp> Cohort. Ann. Neurol. 99, 1014–1029 (2026).
-
Tao, J. et al. Dietary One‑Carbon Nutrients and Genetic Risk in Parkinson’s Disease: A Prospective Cohort Study. J. Gerontol. A Biol. Sci. Med. Sci. https://doi.org/10.1093/gerona/glag048 (2026) doi:10.1093/gerona/glag048.
-
Kolb, H., Kempf, K., Röhling, M., Lenzen-Schulte, M., Schloot, N. C., & Martin, S. (2021). Ketone bodies: from enemy to friend and guardian angel. BMC Medicine 2021 19:1, 19(1), 1–15. https://doi.org/10.1186/S12916-021-02185-0
-
Phillips, Matthew C L et al. “Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.” Movement disorders : official journal of the Movement Disorder Society vol. 33,8 (2018): 1306-1314. doi:10.1002/mds.27390
-
Pokora, B., Pokora, K., Binienda, A. & Fichna, J. The ketogenic diet in Parkinson’s disease: a potential therapeutic strategy. Pharmacological Reports 77, 1491–1513 (2025).
-
Moon, S., Kang, J., Kim, S. H., Chung, H. S., Kim, Y. J., Yu, J. M., Cho, S. T., Oh, C. M., & Kim, T. (2020). Beneficial Effects of Time-Restricted Eating on Metabolic Diseases: A Systemic Review and Meta-Analysis. Nutrients 2020, Vol. 12, Page 1267, 12(5), 1267. https://doi.org/10.3390/NU12051267
-
Neth, Bryan J et al. “The Role of Intermittent Fasting in Parkinson's Disease.” Frontiers in neurology vol. 12 682184. 1 Jun. 2021, doi:10.3389/fneur.2021.682184
-
Parkinson’s Disease- Dr Matthew Phillips: Fasting & Dietary Strategies as Parkinson’s Therapies - YouTube. (n.d.). Retrieved March 24, 2024, from https://www.youtube.com/watch?v=iBNNIIDBIYU
-
Li, T. et al. Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson’s Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism. Advanced Science 13, (2026).
-
Afzal, Obaid et al. “Green Tea Catechins Attenuate Neurodegenerative Diseases and Cognitive Deficits.” Molecules (Basel, Switzerland) vol. 27,21 7604. 6 Nov. 2022, doi:10.3390/molecules27217604
-
Ren, Xiangpeng, and Jiang-Fan Chen. “Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms.” Frontiers in neuroscience vol. 14 602697. 17 Dec. 2020, doi:10.3389/fnins.2020.602697
-
Gao, X et al. “Habitual intake of dietary flavonoids and risk of Parkinson disease.” Neurology vol. 78,15 (2012): 1138-45. doi:10.1212/WNL.0b013e31824f7fc4
-
Eating berries may protect against Parkinson’s disease | News | Harvard T.H. Chan School of Public Health. (n.d.). Retrieved March 25, 2024, from https://www.hsph.harvard.edu/news/hsph-in-the-news/parkinsons-disease-berries-gao/
-
Wang, C., Yang, M., Liu, D., & Zheng, C. (2024). Metabolic rescue of α-synuclein-induced neurodegeneration through propionate supplementation and intestine-neuron signaling in C. elegans. Cell Reports, 43(3), 113865. https://doi.org/10.1016/j.celrep.2024.113865
-
Petrov, V. A. et al. Resistant starch improves Parkinson’s disease symptoms through restructuring of the gut microbiome and modulating inflammation. Brain Behav. Immun. 132, 106217 (2026).
-
Hantikainen, E., Trolle Lagerros, Y., Ye, W., Serafini, M., Adami, H. O., Bellocco, R., & Bonn, S. (2021). Dietary Antioxidants and the Risk of Parkinson Disease: The Swedish National March Cohort. Neurology, 96(6), E895–E903. https://doi.org/10.1212/WNL.0000000000011373
-
Schirinzi, Tommaso et al. “Dietary Vitamin E as a Protective Factor for Parkinson's Disease: Clinical and Experimental Evidence.” Frontiers in neurology vol. 10 148. 26 Feb. 2019, doi:10.3389/fneur.2019.00148
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Akhlaghi, M., Foshati, S., Hashemi Moghaddam, F., Sasani, M. R. & Kazemi, A. Foods and Dietary Intakes and the Risk of Parkinson’s Disease: A Systematic Review and Dose–Response Meta-analysis of Prospective Cohort Studies. Nutr. Rev. https://doi.org/10.1093/nutrit/nuaf224 (2025) doi:10.1093/nutrit/nuaf224.
-
Levodopa Food Interactions & What to Avoid | APDA. (n.d.). Retrieved March 25, 2024, from https://www.apdaparkinson.org/article/levodopa-dosing-and-food-intake/
