These Underlying Sleep Disorders Could Be Harming Your Brain

Nearly one-third of the population fails to get the recommended seven to nine hours of sleep per night.1 For many of us accustomed to functioning on much less sleep, it’s easy to shrug it off and say, “What’s the big deal?” However, sleep is a basic human need, much like food and water.2 Imagine the consequences of ignoring these basic needs, like chronic dehydration and starvation. Alarmingly, many experts in the medical community consider sleep deprivation a growing epidemic. Read on to learn more about chronic sleep deprivation, the underlying sleep disorders that may be to blame, and its lasting impact on cognitive health.
Can’t Sleep? Your Brain’s Critical Functions May Be at Risk
One night of poor sleep won’t ruin your brain, but it’s not entirely harmless. The more nights of sleeplessness you accumulate, the greater the strain on your cognitive ability to think, remember, and regulate emotions. This is because of how hard your brain works while you sleep. In fact, your brain is incredibly active when you’re asleep, working to maintain these functions:
Memory Retention
While you sleep, your brain takes all the information from the day, reinforces the important memories, and filters out the unnecessary moments. It categorizes memories into short-term and long-term storage and prepares you to take in the next day’s information. Studies have demonstrated that sleep deprivation impairs the brain’s ability to effectively process and organize memories, making learning new things and recalling past moments more challenging.3
Emotion Regulation and Stability
It’s no secret that poor sleep plays a significant role in emotional reactions, and evidence supports it. A whole night’s rest allows the brain to process feelings and appropriately respond to the day’s challenges. During REM sleep, the brain strengthens neural connections linked to emotional experiences and enhances stability. A lack of sleep can work against emotional stability and even increase the risk of mental health conditions.4, 5 Besides maintaining stable emotions, sleep is essential to managing and mitigating stress. During sleep, the brain regulates cortisol levels and resets the body’s stress response. Insufficient sleep keeps cortisol high and increases the risk of anxiety burnout.
Energy Restoration
Nothing’s more rejuvenating than a good night’s sleep — and our brains feel the same way! During sleep, the brain transitions into a restorative mode to replenish the energy it uses throughout the day, which is crucial to maintaining important cognitive functions. Sleep deprivation disrupts this process, leading to common symptoms you have probably noticed before, such as poor focus and problem-solving ability. In fact, research has shown that attention is one of the first cognitive functions to suffer from sleep deprivation, as the brain struggles to stay alert and filter out distractions.6 Sleep has a similar effect to a drug; the higher the ’dose’(hours of sleep) you get, the better your attention and cognitive ability. Meanwhile, chronic sleep deprivation can lead to mental fatigue, slow reaction time, and reduced cognitive function. Whether it’s one night of inadequate sleep or months of it, you may feel everyday tasks become more and more difficult.
Toxin Removal
One of the most important processes during sleep is the brain’s natural toxin removal system. Throughout the day, the brain is constantly working to learn, think, and process, which burns energy and, in turn, generates metabolic byproducts. These include beta-amyloid and tau proteins — both linked to Alzheimer’s — in addition to free radicals and damaged molecules.7 Sleep activates the brain’s natural cleaning system, the glymphatic system, and triggers cerebrospinal fluid, or the fluid surrounding the brain, to wash out these toxins.8 This process, also known as autophagy, is closely tied to cerebral blood flow, which increases during deep sleep to help distribute nutrients and remove waste efficiently. When sleep is interrupted, reduced blood flow can hinder this clearance process, allowing harmful substances to accumulate. Suppose we’re not allowing our brains to clean up every night. In that case, we’re permitting the buildup of waste products that can increase the risk of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and other forms of dementia.
The Sleep Disorders that Disrupt Brain Function
For up to 70 million people, poor sleep isn’t just a matter of stress or an ineffective bedtime routine — it’s often an undiagnosed sleep disorder.9 Quality rest is crucial for a healthy brain, but for many people, sleep disorders prevent them from getting the restorative sleep their brains need. Sadly, the effects of chronic sleep deprivation can be detrimental, as long-term sleep issues have been linked to neurodegenerative diseases like dementia .10 So, what are common sleep disorders, and how are they impacting your brain health?
Insomnia is the struggle to fall, stay, or get restful sleep, leading to chronic sleep deprivation. Lack of sleep limits the brain’s ability to remove waste, organize memories, and regulate emotions. Over time, this can become:11
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Trouble concentrating and poor memory recall
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Increased stress and mood instability
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A higher risk of anxiety, depression, and cognitive decline
Sleep Apnea causes repeated pauses in breathing during sleep, resulting in poor oxygen supply to the brain. The brain depends on steady oxygen and uninterrupted sleep cycles. Sleep apnea disrupts both, contributing to:
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Memory and attention problems
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Brain inflammation, which is linked to dementia and Alzheimer’s12
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Increased risk of stroke and other cardiovascular issues13
Restless Leg Syndrome creates an uncontrollable urge to move the legs at night, disrupting sleep quality. Sleep loss from RLS can lead to:
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Poor focus and mental fatigue
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Increased stress and anxiety
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Vascular problems and chronic inflammation, increasing the risk of dementia14
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Disruptions in dopamine levels, which may be linked to Parkinson’s and Alzheimer’s
Narcolepsy is a neurological disorder that interrupts the brain’s ability to correctly regulate sleep-wake cycles, causing sudden sleep attacks and muscle weakness. Narcolepsy interferes with REM sleep, which is vital for learning and emotional stability. This often results in:4
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Emotional instability and mood swings
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Difficulty concentrating and processing information
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Hallucinations or sleep paralysis
Parasomnias are a group of sleep disorders, including sleepwalking, night terrors, and REM sleep behavior disorder, where the brain struggles to transition between sleep stages properly. Parasomnias can cause:15
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Fragmented sleep, reducing memory retention
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Higher stress and emotional instability
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Increased chance of neurodegenerative diseases such as Parkinson’s and dementia
How Do I Know If I Have a Sleep Disorder?
Sleep disorders often go undiagnosed, but warning signs and symptoms like persistent fatigue, trouble sleeping, loud snoring, or unusual nighttime behaviors shouldn’t be ignored. If these symptoms sound familiar, meeting with a doctor or sleep specialist can help you find answers and protect your brain health.
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References
1. Suni, E. & Truong, K. 100+ Sleep Statistics. SleepFoundation.org (2023).
2. What Are Sleep Deprivation and Deficiency? National Heart, Lung, and Blood Institute (2022).
3. Newbury, C. R., Crowley, R., Rastle, K. & Tamminen, J. Sleep deprivation and memory: Meta-analytic reviews of studies on sleep deprivation before and after learning. Psychol Bull 147, 1215–1240 (2021).
4. Goldstein, A. N. & Walker, M. P. The Role of Sleep in Emotional Brain Function. Annu Rev Clin Psychol 10, 679–708 (2014).
5. Minkel, J. D. et al. Sleep deprivation and stressors: Evidence for elevated negative affect in response to mild stressors when sleep deprived. Emotion 12, 1015–1020 (2012).
6. Krause, A. J. et al. The sleep-deprived human brain. Nat Rev Neurosci 18, 404–418 (2017).
7. Bloom, G. S. Amyloid-β and Tau. JAMA Neurol 71, 505 (2014).
8. Wegorzewska, M. Neurons help flush waste out of brain during sleep. WashU Medicine (2024).
9. Deshong, A. & Breus, Dr. M. Sleep Disorders: An Overview. (2024).
10. Sabia, S. et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun 12, 2289 (2021).
11. Insomnia Causes and Risk Factors. National Heart, Lung, and Blood Institute (2022).
12. Carvalho, D. Z. et al. Association of Polysomnographic Sleep Parameters With Neuroimaging Biomarkers of Cerebrovascular Disease in Older Adults With Sleep Apnea. Neurology 101, (2023).
13. Gottesman, R. F. et al. Impact of Sleep Disorders and Disturbed Sleep on Brain Health: A Scientific Statement From the American Heart Association. Stroke 55, (2024).
14. Kim, K. Y. et al. Restless leg syndrome and risk of all-cause dementia: a nationwide retrospective cohort study. Alzheimers Res Ther 15, 46 (2023).
15. Bryan, L. & Cotliar, Dr. D. Parasomnias. SleepFoundation.org (2023).
16. Golmohammadi, M., Attari, V. E., Salimi, Y., Nachvak, S. M. & Samadi, M. The effect of MIND diet on sleep status, anxiety, depression, and cardiometabolic indices in obese diabetic women with insomnia: study protocol for a randomized controlled clinical trial {1}. Trials 25, 660 (2024).
17. Survey Conducted by NeuroReserve. (2022).